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#Depression

Articles tagged #Depression on Vitalspell.

Close-up of vitamin D3 capsules and box on a clean white surface

Vitamin D at 5,000 IU reduced depression symptoms most in new dose-response analysis

A 2026 meta-analysis of 15 RCTs finds vitamin D supplementation significantly reduces depressive symptoms, with 5,000 IU per day showing the greatest effect. Reductions in PTH and TNFα point toward anti-inflammatory mechanisms.

Mira Chen8 min read