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The latest from Hormones on Vitalspell.

Illustration related to perimenopause and heart health

Perimenopause heart risk may rise before menopause ends

Perimenopause heart risk may start climbing before menopause is complete, with new data tying the transition to worse lipid and glucose scores.

Priya Nair6 min read

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Laboratory scientist with test tubes illustrating women's health research
Hormones

Can Allegra and Pepcid ease PMDD and menopause symptoms?

Allegra and Pepcid for menopause and PMDD has a plausible histamine rationale, but evidence is thin and standard PMDD treatments still have stronger support.

Priya Nair
Close-up laboratory-style image suggesting creatine and menopause research
Hormones

Can creatine help during menopause? What the evidence says

Creatine is being pitched as a menopause fix, but the research is narrower: strongest signals are for exercise-linked muscle and bone outcomes, with one small 2026 trial hinting at cognitive benefits.

Priya Nair
Close-up of a patient consulting a doctor with a clipboard in a medical setting.
Hormones

The Lancet Just Renamed PCOS. For 170 Million Women, It Changes Everything

After 14 years of global consensus-building, Polycystic Ovary Syndrome has been renamed Polyendocrine Metabolic Ovarian Syndrome. The new name captures what the condition actually is — and why 70 percent of affected individuals remain undiagnosed.

Priya Nair
Ginkgo leaf and herbal supplement capsules arranged on a marble surface, representing natural adaptogenic supplements
Hormones

Ashwagandha and multi-herb formula both reduced stress in 60-day trial

A 186-person randomized controlled trial published in Trials found that a full-spectrum ashwagandha root extract and a multi-herb adaptogen blend each reduced perceived stress significantly more than placebo over 60 days, with the ashwagandha formula showing the larger effect. Sleep quality, restorative sleep, anxiety, and fatigue also improved, while mental alertness was unchanged.

Priya Nair
Vitex agnus-castus monk's pepper medicinal plant with purple flower spikes and green leaves
Hormones

Vitex agnus-castus improved oxidative stress markers and insulin resistance in PCOS trial

A 12-week randomized controlled trial of 60 women with PCOS found that 5.8 mg daily of standardized Vitex agnus-castus extract improved antioxidant capacity, reduced insulin resistance, and lowered hirsutism scores compared to placebo. The trial was published in JBRA Assisted Reproduction in January 2026.

Priya Nair
Fresh edamame soybeans in a bowl with sea salt on a wooden table — whole soybeans are the richest dietary source of daidzein, genistein, and glycitein, the three isoflavones linked to hot flash reduction in the 2025 trial
Hormones

Soy isoflavones cut severe hot flashes by 92% in 12-week trial

A secondary analysis of a randomized trial found that a low-fat vegan diet supplemented with soybeans reduced severe hot flashes by 92% in postmenopausal women, with daidzein emerging as the main independent predictor. The reduction was not mediated by weight loss.

Priya Nair
Close-up of vibrant saffron threads on a dark surface, the red stigmas arranged in loose clusters
Hormones

Saffron and ginseng improve erectile function, meta-analysis of 14 trials finds

A 2025 systematic review of 14 randomized trials found that saffron and ginseng consistently improved erectile function, while Tribulus terrestris and maca lacked sufficient evidence. The analysis, covering 1,227 men, is the most comprehensive assessment of herbal ED supplements to date.

Priya Nair
Resveratrol supplement capsules on a dark background
Hormones

Resveratrol for menopause: less pain, stronger bones, no cognitive benefit

A 2025 meta-analysis of 10 RCTs with 928 postmenopausal women found resveratrol reduced pain and a bone resorption marker, but cognition, mood, sleep, and metabolism were unaffected.

Priya Nair