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Articles tagged #Diabetes on Vitalspell.

Close-up of yellow herbal powder and dried flowers on a warm-toned surface, representing natural medicinal compounds under scientific investigation

Berberine derivative lowered HbA1c by 1% in 12-week diabetes trial

A phase 2 randomized trial published in JAMA Network Open found that HTD1801, an oral compound combining berberine with ursodeoxycholic acid, reduced HbA1c by 1.0 percentage point over 12 weeks. The drug also improved insulin sensitivity, lipid profiles, and liver enzyme levels, with two phase 3 trials now completed and an NDA submission planned.

Sera Voss6 min read