#Nootropics
Articles tagged #Nootropics on Vitalspell.
Brain health supplements: what the evidence says about what works
Brain health supplements are a multibillion-dollar market built on promises most products cannot back. Only multivitamins and creatine have consistent trial data, while most other products sell on claims the research simply does not support.
Bacopa monnieri outperforms Ginkgo biloba for working memory, analysis finds
A 2026 network meta-analysis of 29 trials found high-dose Bacopa monnieri substantially outperformed Ginkgo biloba for working memory in healthy adults, though the comparison relies on indirect evidence with no head-to-head trials.
Lion's Mane improved visual attention and sleep in 8-week RCT of 109 adults
A new randomized controlled trial posted to medRxiv found that 2 grams of Hericium erinaceus per day improved visual attention, working memory, sleep quality, and mood in adults aged 40 to 75 with subjective cognitive complaints. The effect sizes were modest and the study was funded by the supplement's manufacturer.
Lion's Mane extract showed no overall cognitive improvement in acute trial
A double-blind trial in Frontiers in Nutrition found that a single 3-gram dose of Lion's Mane fruiting body extract did not significantly improve overall cognition or mood in healthy young adults, though fine motor dexterity improved on the pegboard test.