#Nutrition
Articles tagged #Nutrition on Vitalspell.
Vitamin D at 5,000 IU reduced depression symptoms most in new dose-response analysis
A 2026 meta-analysis of 15 RCTs finds vitamin D supplementation significantly reduces depressive symptoms, with 5,000 IU per day showing the greatest effect. Reductions in PTH and TNFα point toward anti-inflammatory mechanisms.
Vitamin B12 and muscle mitochondria: what the latest research reveals
New research from Cornell shows vitamin B12 directly affects skeletal muscle energy production at the mitochondrial level. In aged mice, B12 supplementation doubled a key enzyme's activity, raising questions about whether marginal deficiency contributes to age-related muscle decline.
Nutrition timing alone not enough for night-shift metabolic health, trial finds
An 8-week crossover trial in female healthcare workers found that protein-and-nutrient-timing guidance modestly improved visceral fat percentage but did not shift inflammatory markers, gut microbiome diversity, or mental health scores. The findings suggest dietary changes alone are insufficient to reverse the metabolic effects of circadian disruption.
Magnesium bisglycinate modestly improved insomnia in largest placebo-controlled trial
A four-week randomized trial in 155 adults found that 250 milligrams of magnesium bisglycinate per day modestly reduced insomnia severity compared to placebo. The benefit was largest in people with low dietary magnesium intake.