#Rct
Articles tagged #Rct on Vitalspell.
One Gut Bacterium, Two Kilos Kept Off — But the Trial Was Small
A Nature Medicine RCT found pasteurized Akkermansia muciniphila MucT reduced weight regain by two-thirds compared to placebo across 24 weeks. The mechanism is specific, the effect is real, and the evidence is still incomplete.
Lion's Mane improved visual attention and sleep in 8-week RCT of 109 adults
A new randomized controlled trial posted to medRxiv found that 2 grams of Hericium erinaceus per day improved visual attention, working memory, sleep quality, and mood in adults aged 40 to 75 with subjective cognitive complaints. The effect sizes were modest and the study was funded by the supplement's manufacturer.
Oyster mushrooms preserved mood and cut inflammation in older adults
A crossover trial in Food & Function found that a single serving of oyster mushrooms preserved positive mood and reduced three inflammatory markers compared to placebo over 6 hours, but showed no consistent cognitive benefit in healthy adults aged 60 to 80.
Resveratrol for menopause: less pain, stronger bones, no cognitive benefit
A 2025 meta-analysis of 10 RCTs with 928 postmenopausal women found resveratrol reduced pain and a bone resorption marker, but cognition, mood, sleep, and metabolism were unaffected.
Magnesium bisglycinate modestly improved insomnia in largest placebo-controlled trial
A four-week randomized trial in 155 adults found that 250 milligrams of magnesium bisglycinate per day modestly reduced insomnia severity compared to placebo. The benefit was largest in people with low dietary magnesium intake.