#Aging
Articles tagged #Aging on Vitalspell.

Plasma Exchange Reduced Blood Microplastics 60% in First Human Study
Plasma exchange reduced circulating microplastics ~60% in high-burden patients in the first human study. Whether that improves health is still unknown.

Vitamin B12 and muscle mitochondria: what the latest research reveals
New research from Cornell shows vitamin B12 directly affects skeletal muscle energy production at the mitochondrial level. In aged mice, B12 supplementation doubled a key enzyme's activity, raising questions about whether marginal deficiency contributes to age-related muscle decline.

Limited evidence links creatine to better cognition in older adults
A systematic review of six studies finds creatine may benefit memory and attention in adults over 55. The evidence is thin, with only one of six studies rated methodologically 'good.' The authors say high-quality trials are needed before clinical recommendations.

NMN and NR supplements: what the evidence says about NAD precursors and aging
NAD levels drop by roughly half between age 40 and 70, and supplement companies are selling NMN and NR as the solution. The human trials show measurable NAD increases but inconsistent clinical benefits, and the regulatory situation for NMN remains unsettled.

Oyster mushrooms preserved mood and cut inflammation in older adults
A crossover trial in Food & Function found that a single serving of oyster mushrooms preserved positive mood and reduced three inflammatory markers compared to placebo over 6 hours, but showed no consistent cognitive benefit in healthy adults aged 60 to 80.
