#Vitamin D
Articles tagged #Vitamin D on Vitalspell.
Vitamin D, calcium do not prevent fractures in most older adults
153,902 participants across 69 trials show vitamin D and calcium supplements offer little to no clinically meaningful protection against fractures or falls in older adults.
What a 2026 vitamin D meta-analysis found in multiple sclerosis
A 2026 meta-analysis found a narrow vitamin D signal on MS relapse rates, but no clear overall benefit for disability scores or relapse risk.
Vitamin D at 5,000 IU reduced depression symptoms most in new dose-response analysis
A 2026 meta-analysis of 15 RCTs finds vitamin D supplementation significantly reduces depressive symptoms, with 5,000 IU per day showing the greatest effect. Reductions in PTH and TNFα point toward anti-inflammatory mechanisms.
Vitamin D plus K2 acts like a drug, not a supplement
An Italian cardiology team's narrative review in IJMS reframes combined vitamin D and K2 as a low-potency pharmacological intervention, arguing that the large neutral RCTs tested the wrong populations and ignored K2 as an essential cofactor.